Genova Diagnostics

Genova Diagnostics- comprehensive Urine element for provoked heavy metal testing

The Comprehensive Urine Elements Profile measures urinary excretion of 15 nutrient elements and 20 toxic metals. That include: Classic toxins such as mercury and lead, even new toxics like niobium. If the physician suspects of metal exposure on his patient, also potential nutrient and mineral wasting, this would be the right test to do. .


The Comprehensive Urine Elements Profile offers an advanced, comprehensive assessment of toxic and potentially toxic elements excreted in urine. Additionally, this profile measures elements used in medical, aerospace, nuclear and high-tech electronic industries. .


Sources of Exposure

Accumulations of these toxics can occur in the human body in response to work-related exposures or to environmental exposures from toxic release in air, soil, or industrial waste systems. These sources include::

Fabrication of nuclear reactor fuel assemblies
  Electronics and computer manufacturing
Plating and parts manufacture in aerospace and machine tool industries
Hormonal imbalances

According to the EPA, the U.S. has the largest electronics (including computer) workforce in the world. Exposures to the measured elements can occur in other occupations as well, including:

Welding and metal shaping
Military or police service (with weapons use)
  Handling and disposal of wastes
Oil refining
Manufacture of pigments and coatings
  Petrochemical production

Health Consequences of Exposure

Evidence suggests that chronic toxic element exposure can adversely affect:

Cancer risk
Degenerative conditions

Neurological development and function

The Comprehensive Urine Elements Profile calculates urine excretion of the elements obtain through chronic or acute exposure. All toxic metals are reported as micrograms/g creatinine or as micrograms per 24 hours. With this the physicians can efficiently monitor the detoxification progress and nutrient element status during treatment.

Energy levels
Respiratory, cardiac, hepatic and immune functions
Reproductive function
  Cognitive and emotional health

“Provocative” Urine Testing

Urine can be collected thru an administraion of a "challenge" agents such as: EDTA, DMSA, DMPS, and D-penicillamine, that targets specific toxic elements that helps the physician identify tissue burden from previous exposures. Depending on the agent administered, urine collection may be spot or short-term (2-6 hours), intermediate (8-12 hours) or a complete 24-hour collection. Since many detoxification agents are element-specific, this approach is best utilized when the clinician suspects specific heavy metal toxicities.

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